UniODA vs. Logistic Regression: Serum Cholesterol and Coronary Heart Disease and Mortality Among Middle Aged Diabetic Men

Paul R. Yarnold

Optimal Data Analysis, LLC

The effect of serum cholesterol level on coronary heart disease and mortality was assessed for middle aged diabetic men in a prospective population study.1 Logistic regression was used to test the linear trend over quintiles, yielding estimated p<0.02. However the validity of the estimated Type I error rate is called into question because the minimum expectation for chi-square was violated. UniODA was applied to these data and identified a model yielding moderate classification accuracy (ESS=29.9, exact p<0.0006), which was stable in jackknife validity analysis.

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