Paul R. Yarnold
Optimal Data Analysis, LLC
Lysozyme levels in gastric juice of peptic ulcer patients were compared against normal controls by t-test, finding p<0.05. Because standard deviations differed by a factor of two between groups, and were proportional to the means, analysis of natural logarithms was instead deemed appropriate: the resulting t-test wasn’t statistically significant. Analyzed by ODA no statistically significant between-group difference emerged, and results obtained for raw data and for natural logarithms were identical because ODA results (i.e., p and ESS) are invariant over all monotonic transformations of the data.