FORUM: Pandemic Updates

Linked news articles cover ontogenesis of Pandemic microbes, prevention and mitigation efforts, and substantive repercussions. Some of the linked articles cite topically-relevant scientific publications. Posts are ordered from most (top) to least (bottom) current. (1/20/21) Israel reports single shot of Pfizer vaccine is less effective than was expected: https://www.theguardian.com/world/2021/jan/19/single-covid-vaccine-dose-in-israel-less-effective-than-we-hoped (1/18/21) L452R coronavirus variant was first … Continue reading FORUM: Pandemic Updates

FORUM: Initial Findings of the Oxford-AstraZeneca COVID-19 Vaccine Efficacy Trial Are Confounded

The initial report on concurrent Phase-3 clinical trials assessing safety and efficacy of Oxford-AstraZeneca (Ox-AZ) COVID-19 vaccine is a superb example of Simpson’s Paradox—arguably the greatest threat to validity of statistical analysis in empirical science. I discuss the confounded Ox-AZ analysis in the context of the prevention of paradoxical findings. The Insidious Problem of Simpson’s … Continue reading FORUM: Initial Findings of the Oxford-AstraZeneca COVID-19 Vaccine Efficacy Trial Are Confounded